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Readers Respond: Has your pet ever had a bad reaction to a medication or topical treatment?

Responses: 28

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Has your pet experienced an adverse reaction to a drug or topical product? There were several reports about Promeris in 2008 and flea and tick products in 2009.

The first thing to do is call your vet as soon as possible. It is a good idea to write down any details you can remember - the time and method of administration, what signs were noted, and what time(s) those signs appeared.

Please report your pet's adverse reaction, either via your veterinarian or yourself. It is important to report these events to provide data and alert other veterinarians, regulating agencies and ultimately, to protect other pets.

Frontline Plus

My 3.5 year old healthy Great Pyrenees has used Frontline Plus without incident since I adopted her 1.5 years ago. I have also used Frontline products on my two 10-year-old cats since they were kittens, as well as misc. foster animals. The last time I applied Frontline Plus to my Pyrenees was two days ago and she has a huge second degree chemical burn everywhere that the chemical made contact with her skin. There is a lot of fluid in that vial for 45-88 lb. dogs. I will no longer use topical pesticides because the chance, however small, of a horrible reaction is not worth taking and there are non-toxic alternatives. I suggest that if people use these products they apply them at a time when they can monitor for a sudden reaction and get emergency treatment it is needed. My dog should be running around in the yard and instead she has to lie down and take medicine and wait for this big painful burn to heal. I will say however that Merial, the Frontline manufacturer, has been very courteou
—Guest Liz

Nexgard - Negative Reaction

We tried a new flea and tick medication called Nexgard and our dog is having an extremely negative reaction to it. A couple of hours after giving it to her she became agitated and extremely itchy. After giving her 3 Benadryl she settled down, but continues to itch, is pulling clumps of hair out, and her skin is red and extremely irritated. Her skin “quivers” when we touch her. The vet said she hadn't heard of another dog having this kind of reaction, but said it definitely sounds like an allergic reaction. The manufacturer or the medication is @merial_pet. ‪#‎nexgard‬ Please share this information!
—Guest Dawn

Frontline bad reaction

We used frontline for 6 yrs no did effects, we used frontline plus this year, our mini. Schnauzer became lethargic,won't jump, need to carry her up and downstairs. Drastic change in hours from application. Called vet, couldn't get in over weekend. Kept an alert eye on her, still eating, drinking,no vomiting, but lethargic, won't play, sleeps. By Sunday, began to get energy back, will still not jump up, can do stairs, but only in the morning, needs recover in between. We see vet Monday. No pain in limbs, back, spine, we checked her over. Didn't eat anything odd, only change frontline plus.
—Guest Healing

Lost my cat from Frontline

I put Frontline on six cats, all of whom were healthy and happy eating and running around playing. Patches, about 12 years old started to walk funny after one hour. Washed her off and gave fluids-to flush any Frontline out ... she stumbled and rolled over for 4 days and had to be feed orally with syringe, but bounced back. Tucker, 4 years old, and healthy, was unlucky. He stumbled as well, washed him off, gave him fluids and he tried so hard to walk and eat, his head was bobbing hours later and the vets said it appeared he had some neurological damage. Lab reports were fine except a little high Glucose level. That may have been due to me given him Pediasure by syringe because he wasn't eating. He died 9 days later. The other 4 cats are fine, but Now I will seek alternatives to Frontline.
—Guest Patty

Severe reaction to Frontline for cats

I applied Costco-supplied frontline for cats treatments to my healthy 22 pound Neutered male mix breed cat and within a day he became very lethargic, threw up all his food and developed an inch and a half large bald spot where the medicine was applied. Now I fear using any of these flea treatments for they may cause a very severe allergic reaction.
—Guest Dave

Bem

I gave my 2yr. old male 11# cat Frontline in Dec 2013. Almost immediately he was frothing at the mouth, gagging and drooling. In a few minutes he appeared to be fine and there were no further symptoms. It was purchased from my vet. In Jan. I gave him the Frontline purchased from Costco at a much lower price, w/the same immediate short-lived reactions. Called the vet and was told that it was oke and to go ahead and continue giving it. NO WAY!!!!
—Guest Beth Miller

Kirkland Signature Flea and Tick for Cat

This product put my healthy cat in the vet emergency facility this morning, barely able to breathe. Horrible product with many many many reports of adverse effects including fatalities. Do not use!!!!!!!
—Guest Jeff

Promeris reaction

Shiba Inu 6 years old given May 4, 2012. Lethargic, drooling, stagering, high as a kite! This is her second dose. Gave her a dose w same reaction a year ago- Vet said then after I notified then of the bad reaction first time it was impossible to be from Promeris. Decided to try again - same reaction. I feel like I'm killing my dog-watching her suffer.
—Guest Cyndee

Promeris caused tremors

Day 1 I saw mild tremors when my 2 yr old ACD (Blue Heeler) went to bed with us. Didn't think much of it (thought she was dreaming or something), but the next day they were much worse. Vet said that Collie breeds and Heelers were sensitive to the active ingredient... Now we have to pay for injections of the antidote every 4-6 hours! Thanks for a wonderful product Promeris!
—Guest Jason F

Severe reaction to frontline for cats

I am currently abroad and my boyfriend gave our cat his frontline which we have used on several occasions. This time he has had a severe reaction to it. He is having respiratory problems amongst other things. My boyfriend washed it off within 2 hours of applying it, when he noticed the change in him. It's been 48 hours, within that time he has been to the vets twice and received steroid and antibiotic treatments. Has anyone else's cat had respiratory problems and recovered. I'm so scared and just hoping he will get better asap. My boyfriend said he has drank water and been to the toilet since but now I'm worried about kidney damage/failure.
—Guest Sarah D

Severe reaction to frontline for cats

I am currently abroad and my boyfriend gave our cat his frontline which we have used on several occasions. This time he has had a severe reaction to it. He is having respiratory problems amongst other things. My boyfriend washed it off within 2 hours of applying it, when he noticed the change in him. It's been 48 hours, within that time he has been to the vets twice and received steroid and antibiotic treatments. Has anyone else's cat had respiratory problems and recovered. I'm so scared and just hoping he will get better asap. My boyfriend said he has drank water and been to the toilet since but now I'm worried about kidney damage/failure.
—Guest Sarah D

Promeris Fried my Dog

I used Promeris once in January and then in February. The second month I used this product it Fried my Labs back. So bad, that after $600 in vet bills and 4 visits so far, she still has severe burns and scabs that will not heal. The vet says it was due to Promeris. I called the manufacturer and they seemed indifferent about the side effects. I advise NO ONE use this product on their family pet. The company denies it is from their product and refuses to accept any financial responsibility. They are a bad company and should be taken off the market. My poor dogs suffers every day because of PROMERIS. BAD BAD Product, Buyer Beware !!!
—Guest Matt in Orlando

promeris

My 14 year old dog had a convulsion 24 hours after the first dose of Promeris, which I measured and dosed her by weight. My 4 other dogs had no problems at all. I didn't think it was due to the Promeris until the second time it happened after a second dose a month later, again a convulsion 24 hours after dosing, this time the convulsion was much worse, The vet told me he didn't think it could be the Promeris as I had been so careful about the dose, and that more likely she had a brain tumour. She is fine now, well and happy.I will never give it to her again!!!
—Guest natalie

Bad reaction to Frontline Plus

My moms dog became very anxious and twitchy after having the flea and tick collar on him for about 3 weeks. His appetite is diminished and he is now constantly thirsty and dehydrated. He is not his normal happy go lucky self. After reading everything about Frontline Plus I took the collar off of him and gave him some Benadryl. I will see how he recovers from this. I will not ever, ever put this on him again.
—Guest Etheena

Promeris Reaction

3 hour after using Promeris ( by a vet ) on my ( 6 years old 60 KG) dog she was dizzy and hardly walking for at least 30 hours , after washing her very good with water and soap she started to became ok again. now it is 72 hour after using the Promeris and she is almost well again. i understood that this is a known adverse reaction but i'm sorry that i didn't know it before . i felt like i poisoned my own dog
—Guest hilik
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