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Glossary Term: Thrombocytopenia

By , About.com Guide

Blood vessel and cells - courtesy A.D.A.M.

Blood vessel and cells

courtesy A.D.A.M.
Definition: Thrombocytes are small components in the blood that help with clotting. They are more commonly known as platelets.

The first part of the word, thrombocyto- refers to this type of cell. The second part, -penia, means low or less than normal. Thrombocytopenia is a lower than normal thrombocyte count in the blood. Normal is typically >175,000 cells/ul.

What happens if an animal has thrombocytopenia?
This may be an incidental finding, discovered on routine (or other) bloodwork. Some animals may simply be depressed or not have a good appetite. When this condition is severe (<40,000 cells/ul), it can lead to extra bleeding, swelling and bruising.

How does an animal become thrombocytopenic?
Thrombocytopenia may be immune-mediated (the body destroying its own platelets), a decrease in production (bone marrow disease) or a toxic or infectious agent (parasites, bacteria, drug-induced, etc.). Some of the common causes include:

  • Immune-mediated (the body's immune system destroys its own platelets) There are many potential causes to stimulate the immune system into destroying platelets or other blood components.
  • Anaplasma/Ehrlichia or other rickettsial (a type of bacteria) infections. Ticks are a vector for several diseases that can cause thrombocytopenia and other problems.
  • Bone marrow disease - Platelets are produced in bone marrow. Disease in the marrow slows production of the platelets.
  • Babesia or other parasite infections. Ticks are a vector for several diseases that can cause thrombocytopenia and other problems.
  • Some drugs
  • Some modified-live vaccines (creating immune-mediated pathogenesis)
  • Infection
  • Cancer
  • Disseminated Intravascular Coagulation (DIC)

Treatment of thrombocytopenia
Due to the wide variety of potential causes of this condition, the treatment depends on an accurate diagnosis from your pet's veterinarian.

Veterinary Glossary Index

Pronunciation: Throm-bo-site-o-peen-i-a
Also Known As: low platelet count, thrombocytopenic
Examples:
Henry's pre-neuter bloodwork showed a thrombocytopenia, and the veterinarian decided to diagnose and treat the problem before electing to do surgery and risk extra bleeding.

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