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Nutrition Glossary From Vetri-Science® Laboratories

Ingredient Breakdown And Key Terminology For Pet Nutitional Supplement

By Janet Tobiassen Crosby, DVM, About.com

A study done by Dr. John Lawson at Clemson University found that DMG prevented and reduced the inflammatory response in an arthritis rat model. DMG was 70 percent effective in preventing arthritis versus controls at 30 percent, and DMG slowed the onset of arthritis in those rats that did develop arthritis. DMG can help in joint dysfunction by reducing one of its most debilitating symptoms- inflammation. In fact, Vetri-Science-owned U.S. PATENT 5,026,728 is for anti-inflammatory properties of DMG. Five U.S. Patents on DMG have been awarded to Vetri-Science based on 20 years of extensive research into DMG's role in immune response.

What is Manganese? Manganese is an essential mineral that supports many enzyme controlled reactions. It is required for the enzyme glycosyltransferase, which is essential for the formation of collagen, GAGs and proteoglycans, which are all components of articular cartilage. A lack of manganese can lead to inefficient production of GAGs in the joints.

What Role do Antioxidants Play? Antioxidants are substances that block or inhibit destructive oxidation reactions and inhibit enzymes that cause inflammatory responses.

What is Vitamin C (calcium ascorbate)? Calcium ascorbate is the mineral calcium combined with vitamin C (ascorbic acid). This combination is well-absorbed from the digestive tract. Vitamin C supports the production of collagen and provides protection against damaging free radicals that can degrade connective tissue. Calcium ascorbate has been found to be very beneficial in restoring joint function and connective tissue health. As a mineral, calcium is vital for the formation of strong bones. It is also needed to reduce muscle cramping and for muscular growth and contraction.

What is Vitamin E? Vitamin E helps modulate free radical processes in those with joint dysfunction. It provides antioxidant support, promotes improved circulation, enhances the immune system and supports cardiovascular function.

What is Grape Seed Extract? Grape Seed Extract contains proanthocyanidins that may improve joint flexibility and aid in the rebuilding of connective tissue by decreasing damaging prostaglandins, inhibiting histamine release and decreasing possible tissue damage.

What is Selenium? Selenium inhibits the oxidation of lipids and is a vital antioxidant that enhances the uptake of vitamin E. Selenium also protects the immune system by neutralizing formation of free radicals.

What is Glutathione? Glutathione, the master antioxidant of the cell, increases the effectiveness of the body's other antioxidants. It is involved in various reactions, such as the destruction of free radicals and the detoxification of harmful compounds.

What is Cartilage? Cartilage is the major connective tissue in joints that covers the ends of bones. Cartilage provides smooth surfaces for unrestricted joint movement and acts as the principle shock absorber during times of joint stress. Lubrication and nourishment are essential to its structural integrity. Cartilage is made up of four major components:

  • Collagen (protein)
  • Proteoglycans (a complex of protein and glycosaminoglycans)
  • Water
  • Chondrocytes (cells)
As with all components of the body, joint tissue and cartilage are continually broken down and rebuilt in response to stressors.

What are Synovial Joints? Synovial joints are moveable joints (i.e., knee, wrist, hip, shoulder, neck, back, etc.). Their motion may be different; however, their physiological structure is basically the same.

What is Synovial Fluid? Synovial fluid is necessary for joint lubrication and also provides nutrition to cartilage and carries away waste. Normal lubrication requires viscous (highly resistant) synovial fluid. The viscosity (thickness) of synovial fluid depends on the level of a glycosaminoglycan called hyaluronic acid.

What are Synovial Membranes? Synovial membranes are the inner surface of the joint capsule. They are made up of connective tissue that secrete the lubricating glycosaminoglycans found in the synovial fluid. Age, injury, illness and excess weight directly influence joint destruction and the body's ability to regenerate joint tissue.

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Vetri-Science® Laboratories of Vermont is a proud member of the National Animal Supplement Council.

Gina DePinto
Bylines Public Relations & Marketing
phone 760-436-7630
fax 760-436-7730
cell 760-271-7934
e-mail ginadepinto@earthlink.net

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