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Infectious Canine Hepatitis - Adenovirus

Signs, Diagnosis and Treatment of Adenovirus Infection in Dogs

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About Infectious Canine Hepatitis
This is a contagious disease that can be found worldwide, but is uncommon in areas where dogs are routinely vaccinated. It's severity ranges widely from very mild cases to very serious and sometimes fatal disease.

Cause
Infectious canine hepatitis is caused by a virus called canine adenovirus type 1 (CAV-1).

Risk Factors
Young dogs and unvaccinated dogs are at the highest risk of being infected with the virus causing infectious canine hepatitis. Very young puppies tend to develop the most serious illness.

Signs and Symptoms of Infectious Canine Hepatitis

Infectious canine hepatitis can cause a range of symptoms. Some dogs show very mild symptoms, but in severe cases the disease can be fatal. Symptoms can include any of the following:

  • fever
  • loss of appetite
  • lethargy
  • runny eyes and nose
  • cough
  • vomiting
  • bleeding under the skin, bruising (may be noticed in the mouth)
  • swelling of the head, neck and trunk
  • fluid accumulation in abdomen (ascites)
  • jaundice (yellowish tinge to skin)
  • seizures
  • increases thirst and urination (secondary to kidney damage)
  • bluish clouding of cornea is seen in some animals later on in the course of disease ("hepatitis blue eye")


Diagnosis of Infectious Canine Hepatitis
Various methods are available to test for the presence of the virus causing infections canine hepatitis, or the presence of antibodies to the virus. Blood tests can be suggestive of the diagnosis when combined with the clinical signs, depending on the stages of the disease. A decrease in white blood cells and evidence of liver disease may be evident relatively early in the disease. Other tests such as radiographs and urine tests may also be performed.

Treating Infectious Canine Hepatitis
There is no specific treatment for infectious canine hepatitis so treatment is aimed at managing the symptoms until the virus runs its course. Depending on the severity of illness, hospitalization and intravenous fluid therapy may be necessary. Antibiotics don't treat the virus but may be prescribed to ward off secondary bacterial infections. In severe cases, blood transfusions may be necessary.

Preventing Infectious Canine Hepatitis
Vaccines are available to prevent infectious canine hepatitis and are among the core vaccines recommended for all dogs (the combination vaccines often used for dogs protect against infectious canine hepatitis). Vaccination against a closely related virus, canine adenovirus type 2 (CAV-2 protects against both infectious canine hepatitis (CAV-1) and respiratory illness caused by CAV-2. CAV-2 vaccines are most commonly used to protect against both of these viruses due to the potential for side effects from the CAV-1 vaccine. Your vet will recommend a series of vaccines appropriate for your dog to protect against this and other common canine diseases.


Please note: this article has been provided for informational purposes only. If your pet is showing any signs of illness, please consult a veterinarian as quickly as possible.

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